2-benzyl-4,5-dibromopyridazin-3(2H)-one → 2-Benzyl-4-methoxy-5-bromo-3(2H)-pyridazinone

HRID 381913노트

반응식

HRID 381913 반응식
[CH2:1]([N:8]1[C:13](=[O:14])[C:12](Br)=[C:11]([Br:16])[CH:10]=[N:9]1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.FC(F)(F)CN1[C:25](=[O:26])C(Br)=C(Br)C=N1>CO>[CH2:1]([N:8]1[C:13](=[O:14])[C:12]([O:26][CH3:25])=[C:11]([Br:16])[CH:10]=[N:9]1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

참가 물질

4

반응물 2

HCID 99026992-benzyl-4,5-dibromopyridazin-3(2H)-oneHCID 160910464,5-Dibromo-2-(2,2,2-trifluoroethyl)-2,3-dihydropyridazin-3-one

생성물 1

HCID 219339332-Benzyl-4-methoxy-5-bromo-3(2H)-pyridazinone

시약·촉매·용매 1

HCID 887Methanol용매

실험 절차

2-Benzyl-4-methoxy-5-bromo-3(2H)-pyridazinone is prepared according to the method of Example 83B starting with 2-benzyl-4,5-dibromo-3(2H)-pyridazinone, in place of 2-(2,2,2-trifluoroethyl)-4,5-dibromo-3(2H)-pyridazinone and substituting methanol in place of isopropanol.

출처 및 근거

ORD 기록
ord-9ecbc7b7a9304e28901d437553efaf0e
출처 데이터셋
uspto-grants-2001_10
특허 번호
US06307047B1

반응 노트

불러오는 중…