N-(1(S)-benzyl-2-hydroxyethyl)-3(R)-(3-(biphenyl-4-yI)-1H-pyrrol-1-yl)succinamic acid benzyl ester → 3(R)-[3-(biphenyl-4-yl)-1H-pyrrol-1-yl]-N-(2(R)-hydroxycyclohex-1(R)-yl)succinamic acid benzyl ester

반응식

C(OC(=O)C[C@@H](N1C=[CH:28][C:27]([C:30]2[CH:35]=[CH:34][C:33]([C:36]3[CH:41]=[CH:40][CH:39]=[CH:38][CH:37]=3)=[CH:32][CH:31]=2)=[CH:26]1)C(N[C@@H](CC1C=CC=CC=1)CO)=O)C1C=CC=CC=1.[CH2:43]([O:50][C:51](=[O:72])[CH2:52][C@@H:53]([NH:64][C:65](OC(C)(C)C)=O)[C:54]([NH:56][C@@H:57]1[CH2:62][CH2:61][CH2:60][CH2:59][C@H:58]1[OH:63])=[O:55])[C:44]1[CH:49]=[CH:48][CH:47]=[CH:46][CH:45]=1.C1(C2C=CC=CC=2)C=CC(C2CC(OC)OC2OC)=CC=1>C(O)(=O)C>[CH2:43]([O:50][C:51](=[O:72])[CH2:52][C@@H:53]([N:64]1[CH:65]=[CH:26][C:27]([C:30]2[CH:35]=[CH:34][C:33]([C:36]3[CH:41]=[CH:40][CH:39]=[CH:38][CH:37]=3)=[CH:32][CH:31]=2)=[CH:28]1)[C:54]([NH:56][C@@H:57]1[CH2:62][CH2:61][CH2:60][CH2:59][C@H:58]1[OH:63])=[O:55])[C:44]1[CH:45]=[CH:46][CH:47]=[CH:48][CH:49]=1