Trifluoroacetic acid → N-[2,2-dimethyl-1(S)-(pyridin-4-ylcarbamoyl)propyl]-3(R)-[3-[4-(pyridin-4-yl)phenyl]-1H-pyrrol-1-yl]succinamic acid benzyl ester

반응식

C(OC(=O)C[C@@H](NC(OC(C)(C)C)=O)C([NH:14][C@H:15]([C:20](=[O:23])[NH:21]C)[C:16]([CH3:19])([CH3:18])[CH3:17])=O)C1C=CC=CC=1.FC(F)(F)C(O)=O.Cl.[CH2:41]([O:48][C:49](=[O:72])[CH2:50][C@@H:51]([N:55]1[CH:59]=[CH:58][C:57]([C:60]2[CH:65]=[CH:64][C:63]([C:66]3[CH:71]=[CH:70][N:69]=[CH:68][CH:67]=3)=[CH:62][CH:61]=2)=[CH:56]1)[C:52](O)=[O:53])[C:42]1[CH:47]=[CH:46][CH:45]=[CH:44][CH:43]=1.CN(C(ON1N=[N:88][C:83]2[CH:84]=[CH:85][CH:86]=[CH:87]C1=2)=[N+](C)C)C.[B-](F)(F)(F)F>>[CH2:41]([O:48][C:49](=[O:72])[CH2:50][C@@H:51]([N:55]1[CH:59]=[CH:58][C:57]([C:60]2[CH:61]=[CH:62][C:63]([C:66]3[CH:71]=[CH:70][N:69]=[CH:68][CH:67]=3)=[CH:64][CH:65]=2)=[CH:56]1)[C:52]([NH:14][C@H:15]([C:20](=[O:23])[NH:21][C:85]1[CH:84]=[CH:83][N:88]=[CH:87][CH:86]=1)[C:16]([CH3:19])([CH3:18])[CH3:17])=[O:53])[C:42]1[CH:47]=[CH:46][CH:45]=[CH:44][CH:43]=1