Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Dimethylformamide dimethyl acetal → (E)-ethyl 2-((dimethylamino)methylene)-3-oxopentanoate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Dimethylformamide dimethyl acetal | HCID 78373 | — |
| 반응물 | Ethyl 3-oxovalerate | HCID 78656 | — |
| 용매 | Dimethylformamide | HCID 6228 | — |
| 생성물 | (E)-ethyl 2-((dimethylamino)methylene)-3-oxopentanoate | HCID 11820077 | 100% |
반응 단계
According to Scheme 9 Step 1: A solution of ethyl 3-oxopentanoate (13.9 mmol, 2.00 g) and of 1,1-dimethoxy-N,N-dimethylmethanamine (13.9 mmole, 1.84 mL) in DMF (10 mL) was microwaved for 30 min at 120° C. After evaporation of the solvent, 2.76 g (13.9 mmol) of (E)-ethyl 2-((dimethylamino)methylene)-3-oxopentanoate were obtained and used without further purification.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08524718B2 |
| 출처 데이터셋 | uspto-grants-2013_09 |
| ORD ID | ord-36ed30f54e374bdc94cf8a2fd6430b5a |
| 출처 메모 | uspto-grants-2013_09 |