Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Benzoyl chloride → 1-Benzyl-4-(3,5-dimethylbenzoylamino)-5-imidazolecarboxamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Benzoyl chloride | HCID 7412 | — |
| 반응물 | 3,5-Dimethylbenzoyl Chloride | HCID 81088 | — |
| 반응물 | 1-benzyl-4-amino-1H-imidazole-5-carboxamide | HCID 14000620 | — |
| 생성물 | 1-Benzyl-4-(3,5-dimethylbenzoylamino)-5-imidazolecarboxamide | HCID 18360362 | 91% |
반응 단계
An amidation reaction and post-treatment were carried out according to the conditions of Example 1, using 6.54 g (30.2 mmol) of 4-amino-1-benzyl-5-imidazolecarboxamide prepared in Reference Example 2 and, instead of benzoyl chloride, 3,5-dimethylbenzoyl chloride which was separately prepared by a conventional method, to obtain 9.62 g of 1-benzyl-4-(3,5-dimethylbenzoylamino)-5-imidazolecarboxamide (yield 91%).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06310070B1 |
| 출처 데이터셋 | uspto-grants-2001_10 |
| ORD ID | ord-a6bdc99263694f718cdc586144934036 |
| 출처 메모 | uspto-grants-2001_10 |