Glycine, N-[(1,1-dimethylethoxy)carbonyl]-N-methyl- → 1-(4-t-butylbenzyl)-4-(2-(N-t-butyloxycarbonyl-N-methylamino)acetylamino)-5-imidazolecarboxamide

참여 물질

반응 단계

An amidation reaction and post-treatment were carried out under the same conditions as in Example 17, using 2.50 g (9.18 mmol) of 4-amino-1-(4-t-butylbenzyl)-5-imidazole carboxamide which was prepared in the same manner as in Example 57 and 2-(N-t-butyloxycarbonyl-N-methylamino)acetic acid instead of 3-pyridylacetic acid hydrochloride to obtain 3.27 g of 1-(4-t-butylbenzyl)-4-(2-(N-t-butyloxycarbonyl-N-methylamino)acetylamino)-5-imidazolecarboxamide (yield 80%).

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