Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
3-Fluorobenzoyl chloride → 1-(4-t-Butylbenzyl)-4-(3-fluorobenzoylamino)-5-imidazolecarboxamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 3-Fluorobenzoyl chloride | HCID 74376 | — |
| 반응물 | 4-Amino-1-(4-t-butylbenzyl)-5-imidazolecarboxamide | HCID 18360289 | — |
| 생성물 | 1-(4-t-Butylbenzyl)-4-(3-fluorobenzoylamino)-5-imidazolecarboxamide | HCID 18360186 | 70% |
반응 단계
An amidation reaction and post-treatment were carried out under the same conditions as in Example 1, using 1.54 g (5.65 mmol) of 4-amino-1-(4-t-butylbenzyl)-5-imidazole carboxamide which was prepared in the same manner as in Example 57 and 3-fluorobenzoyl chloride instead of benzoyl chloride to obtain 1.57 g of 1-(4-t-butylbenzyl)-4-(3-fluorobenzoylamino)-5-imidazolecarboxamide (yield 70%).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06310070B1 |
| 출처 데이터셋 | uspto-grants-2001_10 |
| ORD ID | ord-847f5e17d08143969243a6780ae8fd50 |
| 출처 메모 | uspto-grants-2001_10 |