Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Diethyl Ether → (2-acetyl-4-chlorophenoxy)-acetic Acid, 1,1-dimethylethyl Ester
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Diethyl Ether | HCID 3283 | — |
| 반응물 | Potassium Carbonate | HCID 11430 | — |
| 반응물 | 3-Chloro-6-hydroxyacetophenone | HCID 74061 | — |
| 반응물 | tert-Butyl bromoacetate | HCID 79177 | — |
| 용매 | Water | HCID 962 | — |
| 용매 | Dimethylformamide | HCID 6228 | — |
| 생성물 | (2-acetyl-4-chlorophenoxy)-acetic Acid, 1,1-dimethylethyl Ester | HCID 67131695 | — |
반응 단계
A mixture of 1-(5-chloro-2-hydroxyphenyl)-ethanone (2 g), potassium carbonate (1.62 g) and tert-butylbromoacetate (1.73 ml) in DMF (5 ml) was stirred at ambient temperature for 16 h. Diethyl ether and water were added and the organic layer separated, it was washed with water, aqueous potassium carbonate solution, brine, dried (Na2SO4) and the solvent removed in vacuo to give the sub-title compound (2.84 g).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08524715B2 |
| 출처 데이터셋 | uspto-grants-2013_09 |
| ORD ID | ord-e58e506d526849c4b183a9ac5b1d2265 |
| 출처 메모 | uspto-grants-2013_09 |