Hydrochloric Acid → 4[-2-(4-Benzyl-piperidine-1-yl)-ethanesulfonyl]-phenol hydrochloride

참여 물질

반응 조건

반응 단계

To a solution of 1.15 g 4[-2-(4-benzyl-piperidine-1-yl)-ethanesulfonyl]-phenol (3.2 mmol) in EtOH (5 ml) was added ethanolic HCl (2.6 ml, 1.46 M, 3.8 mmol). The reaction mixture was cooled to 0-5° C. and stirred for 10 min. Then diethyl ether was added until the product precipitated. After filtration 1.14 g of the product (2.9 mmol, 91%) as a white solid was obtained.

출처 및 근거