4-(2-Chloro-ethanesulfonyl)-phenol → HCID 10221939, 화합물

HRID 382784

반응식

HRID 382784 반응식
Cl[CH2:2][CH2:3][S:4]([C:7]1[CH:12]=[CH:11][C:10]([OH:13])=[CH:9][CH:8]=1)(=[O:6])=[O:5].[CH3:14][C:15]1[CH:28]=[CH:27][C:18]([CH2:19][C@@H:20]2[CH2:25][CH2:24][NH:23][CH2:22][C@@H:21]2[OH:26])=[CH:17][CH:16]=1>>[OH:13][C:10]1[CH:11]=[CH:12][C:7]([S:4]([CH2:3][CH2:2][N:23]2[CH2:24][CH2:25][C@H:20]([CH2:19][C:18]3[CH:27]=[CH:28][C:15]([CH3:14])=[CH:16][CH:17]=3)[C@H:21]([OH:26])[CH2:22]2)(=[O:6])=[O:5])=[CH:8][CH:9]=1

참가 물질

3

반응물 2

HCID 98132494-(2-Chloro-ethanesulfonyl)-phenolHCID 57021598HCID 57021598, 화합물

생성물 1

HCID 10221939HCID 10221939, 화합물수율 31%

실험 절차

The title compound was prepared from 4-(2-chloro-ethanesulfonyl)-phenol and (3R,4R)-4-(4-methyl-benzyl)-piperidin-3-ol in 31% yield as a white foam.

출처 및 근거

ORD 기록
ord-672a9592bbc64974b1d1bc653bcc90a1
출처 데이터셋
uspto-grants-2001_10
특허 번호
US06310213B1

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