[4-(N-tert-butoxycarbonyl-(R)-thiazolidin-4-ylcarbonyl)amino-2-phenylbenzoyl]methionine methyl ester → [4-((R)-thiazolidin-4-ylmethyl)amino-2-phenylbenzoyl]methionine methyl ester
반응식
[CH3:1][O:2][C:3](=[O:38])[C@H:4]([CH2:34][CH2:35][S:36][CH3:37])[NH:5][C:6](=[O:33])[C:7]1[CH:12]=[CH:11][C:10]([NH:13][CH2:14][C@@H:15]2[CH2:19][S:18][CH2:17][N:16]2C(OC(C)(C)C)=O)=[CH:9][C:8]=1[C:27]1[CH:32]=[CH:31][CH:30]=[CH:29][CH:28]=1.COC(=O)[C@H](CCSC)NC(=O)C1C=CC(NC([C@@H]2CSCN2C(OC(C)(C)C)=O)=O)=CC=1C1C=CC=CC=1>>[CH3:1][O:2][C:3](=[O:38])[C@H:4]([CH2:34][CH2:35][S:36][CH3:37])[NH:5][C:6](=[O:33])[C:7]1[CH:12]=[CH:11][C:10]([NH:13][CH2:14][C@@H:15]2[CH2:19][S:18][CH2:17][NH:16]2)=[CH:9][C:8]=1[C:27]1[CH:28]=[CH:29][CH:30]=[CH:31][CH:32]=1참가 물질
3
반응물 2
생성물 1
실험 절차
The desired compound was prepared according to the method of Example 164C, except substituting [4-(N-tert-butoxycarbonyl-(R)-thiazolidin-4-ylmethyl)amino-2-phenylbenzoyl]methionine methyl ester, prepared as in Example 166B, for [4-(N-tert-butoxycarbonyl-(R)-thiazolidin-4-ylcarbonyl)amino-2-phenylbenzoyl]methionine methyl ester.