Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Azetidine → Azetidin-1-yl(7-(4-benzylpiperazin-1-yl)benzofuran-2-yl)methanone
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Azetidine | HCID 10422 | — |
| 반응물 | 7-(4-Benzyl-piperazin-1-yl)-benzofuran-2-carboxylic acid ethyl ester | HCID 59636745 | — |
| 생성물 | Azetidin-1-yl(7-(4-benzylpiperazin-1-yl)benzofuran-2-yl)methanone | HCID 59636710 | — |
반응 단계
The compound was prepared according to the procedure disclosed in Example 39c starting from ethyl 7-(4-benzylpiperazin-1-yl)benzofuran-2-carboxylate (1.0 g, 2.74 mmol) (Example 39b) and azetidine (0.20 mL, 3.02 mmol). Yield: 0.52 g (51%).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08367676B2 |
| 출처 데이터셋 | uspto-grants-2013_02 |
| ORD ID | ord-bb7a6692190b4e0a8be926f7b682478f |
| 출처 메모 | uspto-grants-2013_02 |