Ethyl 1-benzyl-4-(2-chloroethyl)azepane-4-carboxylate → HCID 86641067, 화합물

HRID 383947노트

반응식

HRID 383947 반응식
[CH2:1]([N:8]1[CH2:14][CH2:13][CH2:12][C:11]([CH2:20][CH2:21][Cl:22])([C:15]([O:17][CH2:18][CH3:19])=[O:16])[CH2:10][CH2:9]1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1>CC#N>[Cl-:22].[CH2:1]([N+:8]12[CH2:21][CH2:20][C:11]([C:15]([O:17][CH2:18][CH3:19])=[O:16])([CH2:10][CH2:9]1)[CH2:12][CH2:13][CH2:14]2)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

참가 물질

3

반응물 1

HCID 59291310Ethyl 1-benzyl-4-(2-chloroethyl)azepane-4-carboxylate

생성물 1

HCID 86641067HCID 86641067, 화합물수율 100%

시약·촉매·용매 1

HCID 6342Acetonitrile용매

실험 절차

A solution of ethyl 1-benzyl-4-(2-chloroethyl)azepane-4-carboxylate (4.1 g) in MeCN (200 mL) was stirred at 40° C. for 10 hours. The reaction mixture was concentrated under reduced pressure to obtain 1-benzyl-5-(ethoxycarbonyl)-1-azoniabicyclo[3.2.2]nonane chloride (4.1 g) as a colorless oily substance.

후처리

  1. concentrationThe reaction mixture was concentrated under reduced pressure

출처 및 근거

ORD 기록
ord-61abf6fcafcb4998ac791364c8ce26fd
출처 데이터셋
uspto-grants-2013_02
특허 번호
US08367696B2

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