HCID 86641942, 화합물 → HCID 67272423, 화합물

HRID 384119노트

반응식

HRID 384119 반응식
Cl[C:2]1[N:7]=[C:6]([CH2:8][OH:9])[C:5]([O:10][C:11]2[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=2)=[CH:4][CH:3]=1>C(O)C.[C].[Pd]>[O:10]([C:5]1[C:6]([CH2:8][OH:9])=[N:7][CH:2]=[CH:3][CH:4]=1)[C:11]1[CH:12]=[CH:13][CH:14]=[CH:15][CH:16]=1

참가 물질

4

반응물 1

HCID 86641942HCID 86641942, 화합물

생성물 1

HCID 67272423HCID 67272423, 화합물

시약·촉매·용매 2

HCID 178418390HCID 178418390, 화합물촉매HCID 702Ethanol용매

실험 절차

To a solution of (6-chloro-3-phenoxypyridin-2-yl)methanol (88 mg) in ethanol (1.5 ml), 10 mg of 10% palladium-carbon catalyst was added, and the reaction solution was stirred for 20 hours under hydrogen atmosphere. The catalyst was filtered off through Celite, and the filtrate was distilled off under reduced pressure to afford the title compound as a yellow solid.

후처리

  1. filtrationThe catalyst was filtered off through Celite
  2. distillationthe filtrate was distilled off under reduced pressure

출처 및 근거

ORD 기록
ord-bd62ea0b8b5c446fa104de0383a94650
출처 데이터셋
uspto-grants-2013_02
특허 번호
US08367708B2

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