Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Pentyl chloroformate → Pentyl [(3-methyl-4-oxo-1,4-dihydroquinolin-2-yl)methyl]carbamate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Pentyl chloroformate | HCID 69489 | — |
| 반응물 | 2-(aminomethyl)-3-methylquinolin-4(1H)-one dihydrochloride | HCID 68510759 | — |
| 용매 | Pyridine | HCID 1049 | — |
| 생성물 | Pentyl [(3-methyl-4-oxo-1,4-dihydroquinolin-2-yl)methyl]carbamate | HCID 59526959 | 56.1% |
반응 단계
To a solution of 2-(aminomethyl)-3-methylquinolin-4(1H)-one dihydrochloride (160 mg) in pyridine (8 mL) was added pentyl chloroformate (100 mg), followed by stirring at room temperature for 6 hours. The solvent was evaporated under reduced pressure, and the residue was purified by silica gel chromatography (eluent: chloroform/methanol) to obtain pentyl [(3-methyl-4-oxo-1,4-dihydroquinolin-2-yl)methyl]carbamate (104 mg).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08367702B2 |
| 출처 데이터셋 | uspto-grants-2013_02 |
| ORD ID | ord-0fadd6803b19479cb0949f9f31d07a64 |
| 출처 메모 | uspto-grants-2013_02 |