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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 384574생성일: 2026년 10월 25일

2-Ethoxy-2-oxoethyl 2-butyl-4-chloro-1-{[2'-(1-trityl-1H-tetrazol-5-yl)biphenyl-4-yl]methyl}-1H-imidazole-5-carboxylate → HCID 178441701, 화합물

https://huagongshe.com/reaction/384574

반응식

참여 물질

역할이름HCID투입량
반응물2-Ethoxy-2-oxoethyl 2-butyl-4-chloro-1-{[2'-(1-trityl-1H-tetrazol-5-yl)biphenyl-4-yl]methyl}-1H-imidazole-5-carboxylateHCID 67979259—
용매Hydrochloric AcidHCID 313—
생성물HCID 178441701HCID 178441701—

반응 조건

온도100 °C

반응 단계

2-Ethoxy-2-oxoethyl 2-butyl-4-chloro-1-{[2′-(1-trityl-1H-tetrazol-5-yl)biphenyl-4-yl]methyl}-1H-imidazole-5-carboxylate (1130 mg, 1.48 mmol) was dissolved in concentrated hydrochloric acid (24 mL). The solution was stirred at 100° C. for 30 minutes. The solution was washed with diethyl ether (2×) and the aqueous layer was concentrated in vacuo. The residue was used crude in the following step. LC-MS: m/z 495.0 (M+H).

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US08367711B2
출처 데이터셋uspto-grants-2013_02
ORD IDord-15a211b0ad824bbc8bada56abf249e52
출처 메모uspto-grants-2013_02