5-Bromo-2-iodotoluene → 3-(4-Bromo-2-methyl-phenyl)-5-fluoro-pyridine

HRID 384873

반응식

HRID 384873 반응식
[Br:1][C:2]1[CH:3]=[CH:4][C:5](I)=[C:6]([CH3:8])[CH:7]=1.[F:10][C:11]1[CH:12]=[C:13](B(O)O)[CH:14]=[N:15][CH:16]=1>>[Br:1][C:2]1[CH:3]=[CH:4][C:5]([C:13]2[CH:14]=[N:15][CH:16]=[C:11]([F:10])[CH:12]=2)=[C:6]([CH3:8])[CH:7]=1

참가 물질

3

반응물 2

HCID 27246015-Bromo-2-iodotolueneHCID 44717403(5-Fluoropyridin-3-yl)boronic acid

생성물 1

HCID 684099483-(4-Bromo-2-methyl-phenyl)-5-fluoro-pyridine

실험 절차

The title compound was prepared from 5-bromo-2-iodotoluene and 5-fluoropyridine-3-boronic acid in analogy to Example 1b): MS (ISP): 265.8 and 267.9 (M+H)+.

출처 및 근거

ORD 기록
ord-6fd71ae0629f40fcba69883a937a761d
출처 데이터셋
uspto-grants-2013_02
특허 번호
US08367838B2

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