Tetrahydro-4H-pyran-4-ol → 4-(4-Bromo-2,6-difluoro-phenoxy)-tetrahydro-pyran

HRID 384879

반응식

HRID 384879 반응식
[Br:1][C:2]1[CH:7]=[C:6]([F:8])[C:5]([OH:9])=[C:4]([F:10])[CH:3]=1.[O:11]1[CH2:16][CH2:15][CH:14](O)[CH2:13][CH2:12]1>>[Br:1][C:2]1[CH:7]=[C:6]([F:8])[C:5]([O:9][CH:14]2[CH2:15][CH2:16][O:11][CH2:12][CH2:13]2)=[C:4]([F:10])[CH:3]=1

참가 물질

3

반응물 2

HCID 74956Tetrahydro-4H-pyran-4-olHCID 27362924-Bromo-2,6-difluorophenol

생성물 1

HCID 684092764-(4-Bromo-2,6-difluoro-phenoxy)-tetrahydro-pyran

실험 절차

The title compound was prepared from 4-bromo-2,6-difluorophenol and tetrahydro-4H-pyran-4-ol in analogy to Example 9c): MS (EI): 292 and 294 M+.

출처 및 근거

ORD 기록
ord-caf70b5253454db490934fa4fd423ba1
출처 데이터셋
uspto-grants-2013_02
특허 번호
US08367838B2

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