Tetrahydrofurfuryl alcohol → 2-[(4-Bromo-3-fluorophenoxy)methyl]oxolane

반응식

[Br:1][C:2]1[CH:7]=[CH:6][C:5]([OH:8])=[CH:4][C:3]=1[F:9].O[CH2:11][CH:12]1[CH2:16][CH2:15][CH2:14][O:13]1>>[Br:1][C:2]1[CH:7]=[CH:6][C:5]([O:8][CH2:11][CH:12]2[CH2:16][CH2:15][CH2:14][O:13]2)=[CH:4][C:3]=1[F:9]

참가 물질

반응물 2

HCID 7360Tetrahydrofurfuryl alcohol

HCID 27791534-Bromo-3-fluorophenol

생성물 1

HCID 652031072-[(4-Bromo-3-fluorophenoxy)methyl]oxolane

실험 절차

The title compound was prepared from 4-bromo-3-fluorophenol and rac-2-hydroxymethyl-tetrahydrofuran in analogy to Example 9c): MS (EI): 274 and 276 M+.

출처 및 근거

ORD 기록: ord-148f71d276d34e4088edbb7734754238
출처 데이터셋: uspto-grants-2013_02
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US08367838B2

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