4-Bromo-3-fluorophenol → Rac-2-(4-bromo-3-fluoro-phenoxymethyl)-oxetane

HRID 384887노트

반응식

HRID 384887 반응식
[Br:1][C:2]1[CH:7]=[CH:6][C:5]([OH:8])=[CH:4][C:3]=1[F:9].O[CH2:11][CH:12]1[CH2:15][CH2:14][O:13]1>>[Br:1][C:2]1[CH:7]=[CH:6][C:5]([O:8][CH2:11][CH:12]2[CH2:15][CH2:14][O:13]2)=[CH:4][C:3]=1[F:9]

참가 물질

3

반응물 2

HCID 27791534-Bromo-3-fluorophenolHCID 12284142(Oxetan-2-yl)methanol

생성물 1

HCID 68409002Rac-2-(4-bromo-3-fluoro-phenoxymethyl)-oxetane

실험 절차

The title compound was prepared from 4-bromo-3-fluorophenol and rac-2-hydroxymethyl-oxetane in analogy to Example 9c): MS (EI): 260 and 262 M+.

출처 및 근거

ORD 기록
ord-226713f88ae14294b2d912f3eff99f4f
출처 데이터셋
uspto-grants-2013_02
특허 번호
US08367838B2

반응 노트

불러오는 중…