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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 384912생성일: 2026년 10월 26일

3-(4-Bromo-2-methyl-phenyl)-5-fluoro-pyridine → Rac-[1-(3,4-dichloro-phenyl)-2-[4-(5-fluoro-pyridin-3-yl)-3-methyl-phenyl]-2-oxo-ethyl]-carbamic acid tert-butyl ester

https://huagongshe.com/reaction/384912

반응식

참여 물질

역할이름HCID투입량
반응물3-(4-Bromo-2-methyl-phenyl)-5-fluoro-pyridineHCID 68409948—
반응물Rac-[(3,4-dichloro-phenyl)-(methoxy-methyl-carbamoyl)-methyl]-carbamic acid tert-butyl esterHCID 87442373—
생성물Rac-[1-(3,4-dichloro-phenyl)-2-[4-(5-fluoro-pyridin-3-yl)-3-methyl-phenyl]-2-oxo-ethyl]-carbamic acid tert-butyl esterHCID 68408672—

반응 단계

The title compound was prepared from rac-[(3,4-dichloro-phenyl)-(methoxy-methyl-carbamoyl)-methyl]-carbamic acid tert-butyl ester (Intermediate 9) and 3-(4-bromo-2-methyl-phenyl)-5-fluoro-pyridine (Intermediate 12) in analogy to Example 1a): MS (ISP): 489.2 and 491.1 (M+H)+.

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US08367838B2
출처 데이터셋uspto-grants-2013_02
ORD IDord-66efa25ca539409cbe14d2d9df339209
출처 메모uspto-grants-2013_02