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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 384935생성일: 2026년 10월 26일

(4-Bromophenoxy)(tert-butyl)dimethylsilane → Rac-[2[4-(tert-butyl-dimethyl-silanyloxy)-phenyl]-1-(3,4-dichloro-phenyl)-2-oxo-ethyl]-carbamic acid tert-butyl ester

https://huagongshe.com/reaction/384935

반응식

참여 물질

역할이름HCID투입량
반응물(4-Bromophenoxy)(tert-butyl)dimethylsilaneHCID 4227167—
반응물Rac-[(3,4-dichloro-phenyl)-(methoxy-methyl-carbamoyl)-methyl]-carbamic acid tert-butyl esterHCID 87442373—
생성물Rac-[2[4-(tert-butyl-dimethyl-silanyloxy)-phenyl]-1-(3,4-dichloro-phenyl)-2-oxo-ethyl]-carbamic acid tert-butyl esterHCID 68408872—

반응 단계

The title compound was prepared from rac-[(3,4-dichloro-phenyl)-(methoxy-methyl-carbamoyl)-methyl]-carbamic acid tert-butyl ester (Intermediate 9) and (4-bromo-phenoxy)-tert-butyl-dimethyl-silane in analogy to Example 1a): MS (ISP): 510.3 and 512.2 (M+H)+, 410.1 and 412.1 ((M-Boc)+H)+ (100%).

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US08367838B2
출처 데이터셋uspto-grants-2013_02
ORD IDord-5273946c20e14dd9bfe93e86099fa1f3
출처 메모uspto-grants-2013_02