4-Bromodiphenyl Ether → Rac-[1-(3,4-dichloro-phenyl)-2-oxo-2-(4-phenoxy-phenyl)-ethyl]-carbamic acid tert-butyl ester

HRID 384963

반응식

HRID 384963 반응식
[C:1]([O:5][C:6](=[O:23])[NH:7][CH:8]([C:15]1[CH:20]=[CH:19][C:18]([Cl:21])=[C:17]([Cl:22])[CH:16]=1)[C:9](=[O:14])N(OC)C)([CH3:4])([CH3:3])[CH3:2].Br[C:25]1[CH:30]=[CH:29][C:28]([O:31][C:32]2[CH:37]=[CH:36][CH:35]=[CH:34][CH:33]=2)=[CH:27][CH:26]=1>>[C:1]([O:5][C:6](=[O:23])[NH:7][CH:8]([C:15]1[CH:20]=[CH:19][C:18]([Cl:21])=[C:17]([Cl:22])[CH:16]=1)[C:9](=[O:14])[C:35]1[CH:36]=[CH:37][C:32]([O:31][C:28]2[CH:29]=[CH:30][CH:25]=[CH:26][CH:27]=2)=[CH:33][CH:34]=1)([CH3:2])([CH3:3])[CH3:4]

참가 물질

3

반응물 2

HCID 75654-Bromodiphenyl EtherHCID 87442373Rac-[(3,4-dichloro-phenyl)-(methoxy-methyl-carbamoyl)-methyl]-carbamic acid tert-butyl ester2회

생성물 1

HCID 68408309Rac-[1-(3,4-dichloro-phenyl)-2-oxo-2-(4-phenoxy-phenyl)-ethyl]-carbamic acid tert-butyl ester

실험 절차

The title compound was prepared from rac-[(3,4-dichloro-phenyl)-(methoxy-methyl-carbamoyl)-methyl]-carbamic acid tert-butyl ester (Intermediate 9) and 1-bromo-4-phenoxy-benzene in analogy to Example 1a): MS (ISP): 472.0 (M+H)+.

출처 및 근거

ORD 기록
ord-76d7d4654522401ca7e418f93e3fc780
출처 데이터셋
uspto-grants-2013_02
특허 번호
US08367838B2

연결된 노트

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