Formaldehyde → Benzothiazoline

HRID 385003노트

반응식

HRID 385003 반응식
[CH2:1]=O.[NH2:3][C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][C:5]=1[SH:10]>O.C(OC(C)C)(C)C>[S:10]1[C:5]2[CH:6]=[CH:7][CH:8]=[CH:9][C:4]=2[NH:3][CH2:1]1

참가 물질

5

반응물 2

HCID 712FormaldehydeHCID 87132-Aminothiophenol

생성물 1

HCID 96588Benzothiazoline

시약·촉매·용매 2

HCID 962Water용매HCID 7914Diisopropyl Ether용매

실험 절차

37% formalin (5.2 mL) was diluted with water (80 mL), and diisopropylether (80 mL) and 2-aminobenzenethiol (7.84 g) were added, and then the mixture was stirred at mom temperature for 30 minutes. The organic layer was separated and the aqueous layer was extracted with diisopropylether. The organic layers were combined, washed with saturated brine and then dried over anhydrous sodium sulfate. The solvent was distilled off under reduced pressure and the obtained residue was used for the synthesis of (c).

후처리

  1. additionwere added
  2. customThe organic layer was separated
  3. extractionthe aqueous layer was extracted with diisopropylether
  4. washwashed with saturated brine
  5. dry with materialdried over anhydrous sodium sulfate
  6. distillationThe solvent was distilled off under reduced pressure
  7. customthe obtained residue was used for the synthesis of (c)

출처 및 근거

ORD 기록
ord-4cda6bdfc23841e0bd7e15558c15bc40
출처 데이터셋
uspto-grants-2013_02
특허 번호
US08367843B2

반응 노트

불러오는 중…