Iodine → Muconic Acid

HRID 385194

반응식

HRID 385194 반응식
[C:1]([OH:10])(=[O:9])/[CH:2]=[CH:3]\[CH:4]=[CH:5]\[C:6]([OH:8])=[O:7].II>C(#N)C>[C:1]([OH:10])(=[O:9])/[CH:2]=[CH:3]/[CH:4]=[CH:5]/[C:6]([OH:8])=[O:7]

참가 물질

4

반응물 2

HCID 807IodineHCID 5280614(2E,4Z)-2,4-Hexadienedioic acid

생성물 1

HCID 5356793Muconic Acid수율 80%

시약·촉매·용매 1

HCID 6342Acetonitrile용매

실험 절차

A mixture containing cis,trans muconic acid (1.00 g), a catalytic amount of iodine (53 mg, 3.0 mole percent), and acetonitrile (35 ml) is heated to reflux for 11 hours. The reaction is performed in the presence of ambient light in the laboratory. After cooling to room temperature, the precipitated solid is filtered off and washed with acetonitrile. After drying under high vacuum, 0.80 g (80 percent yield) of pure trans,trans muconic acid are present as a tan-colored powder. The material obtained by this procedure from cis,trans muconic acid is identical to the material obtained from cis,cis muconic acid by the previous procedure.

후처리

  1. temperatureto reflux for 11 hours
  2. filtrationthe precipitated solid is filtered off
  3. washwashed with acetonitrile

출처 및 근거

ORD 기록
ord-8fcd241a22504c1c9f488b368d06e5ab
출처 데이터셋
uspto-grants-2013_02
특허 번호
US08367858B2

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