Trimethyl cyclohex-5-ene-1,2,4-tricarboxylate → Trimethyl cyclohexane-1,2,4-tricarboxylate

HRID 385204노트

반응식

HRID 385204 반응식
[CH:1]1([C:15]([O:17][CH3:18])=[O:16])[CH:6]=[CH:5][CH:4]([C:7]([O:9][CH3:10])=[O:8])[CH2:3][CH:2]1[C:11]([O:13][CH3:14])=[O:12].[H][H]>C(Cl)Cl.[Pd]>[CH:1]1([C:15]([O:17][CH3:18])=[O:16])[CH2:6][CH2:5][CH:4]([C:7]([O:9][CH3:10])=[O:8])[CH2:3][CH:2]1[C:11]([O:13][CH3:14])=[O:12]

참가 물질

5

반응물 2

HCID 60136166Trimethyl cyclohex-5-ene-1,2,4-tricarboxylateHCID 178418361HCID 178418361, 화합물

생성물 1

HCID 12616206Trimethyl cyclohexane-1,2,4-tricarboxylate

시약·촉매·용매 2

HCID 23938Palladium촉매HCID 6344Dichloromethane용매

실험 절차

A solution of trimethyl cyclohex-5-ene-1,2,4-tricarboxylate (0.50 g, 1.9 mmol) in methylene chloride (15 ml) containing a catalytic amount of palladium on carbon (150 mg, 5 percent Pd/C, 7.5 mg Pd, 4 mole percent) is stirred at room temperature under balloon pressure of hydrogen gas for 2 hours, at which point GC-MS analysis shows complete conversion. Filtration and removal of the solvent provides trimethyl cyclohexane-1,2,4-tricarboxylate as a clear, colorless gel (0.42 g, 1.6 mmol, 85 percent yield).

후처리

  1. filtrationFiltration and removal of the solvent

출처 및 근거

ORD 기록
ord-cbb56c265baa494b8a9c6692b82d9022
출처 데이터셋
uspto-grants-2013_02
특허 번호
US08367858B2

반응 노트

불러오는 중…