Benzyl[3-(aminocarbonyl)-5-iodo-2-thienyl]carbamate → 2-Amino-5-(2-fluorophenyl)thiophene-3-carboxamide

HRID 385698노트

반응식

HRID 385698 반응식
C(OC(=O)NC1SC(I)=CC=1C(N)=O)C1C=CC=CC=1.C(OC(=O)[NH:30][C:31]1[S:32][C:33]([C:39]2[CH:44]=[CH:43][CH:42]=[CH:41][C:40]=2[F:45])=[CH:34][C:35]=1[C:36]([NH2:38])=[O:37])C1C=CC=CC=1>>[NH2:30][C:31]1[S:32][C:33]([C:39]2[CH:44]=[CH:43][CH:42]=[CH:41][C:40]=2[F:45])=[CH:34][C:35]=1[C:36]([NH2:38])=[O:37]

참가 물질

3

반응물 2

HCID 59525870Benzyl[3-(aminocarbonyl)-5-iodo-2-thienyl]carbamateHCID 59526021Benzyl[3-(aminocarbonyl)-5-(2-fluorophenyl)-2-thienyl]carbamate

생성물 1

HCID 99646972-Amino-5-(2-fluorophenyl)thiophene-3-carboxamide

실험 절차

The title compound was prepared as described in Intermediate 1 Step 4 using benzyl[3-(aminocarbonyl)-5-(2-fluorophenyl)-2-thienyl]carbamate (1.39 g, 3.74 mmol) as the starting material.

출처 및 근거

ORD 기록
ord-737477e68d65454d86d8846b6cd121df
출처 데이터셋
uspto-grants-2013_02
특허 번호
US08367706B2

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