Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Hydrazinecarboxaldehyde → 5-(4-Bromophenyl)-1H-1,2,4-triazole
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Hydrazinecarboxaldehyde | HCID 12229 | — |
| 반응물 | Ethyl 4-bromobenzene-1-carboximidate | HCID 10466301 | — |
| 용매 | O-Xylene | HCID 7237 | — |
| 생성물 | 5-(4-Bromophenyl)-1H-1,2,4-triazole | HCID 46948734 | — |
반응 단계
Into a 1000 mL 3-necked flask, was placed a solution of ethyl 4-bromobenzenecarboximidoate (54.0 g, 237 mmol) in xylene (500 mL) To the mixture was added NH2NHCHO (14.22 g, 237 mmol). The resulting solution was heated to reflux overnight. The reaction mixture was cooled in an ice bath and filtered. The solid was washed with 700 mL of petroleum ether and dried in an oven under reduced pressure to afford 3-(4-bromophenyl)-1H-1,2,4-triazole (crude) as a white solid.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08367706B2 |
| 출처 데이터셋 | uspto-grants-2013_02 |
| ORD ID | ord-a6dfce0089d44b1f9ed693d88e2046e9 |
| 출처 메모 | uspto-grants-2013_02 |