2-(6-Bromopyridin-2-yl)-2-morpholin-4-ylethanol → HCID 59525794, 화합물
반응식
Br[C:2]1[N:7]=[C:6]([CH:8]([N:11]2[CH2:16][CH2:15][O:14][CH2:13][CH2:12]2)[CH2:9][OH:10])[CH:5]=[CH:4][CH:3]=1.[NH2:17][C:18]1[S:19][C:20]([C:26]2[CH:31]=[CH:30][C:29]([C:32]([OH:35])([CH3:34])[CH3:33])=[CH:28][CH:27]=2)=[CH:21][C:22]=1[C:23]([NH2:25])=[O:24]>>[OH:35][C:32]([C:29]1[CH:28]=[CH:27][C:26]([C:20]2[S:19][C:18]([NH:17][C:2]3[CH:3]=[CH:4][CH:5]=[C:6]([CH:8]([N:11]4[CH2:16][CH2:15][O:14][CH2:13][CH2:12]4)[CH2:9][OH:10])[N:7]=3)=[C:22]([C:23]([NH2:25])=[O:24])[CH:21]=2)=[CH:31][CH:30]=1)([CH3:34])[CH3:33]참가 물질
3
실험 절차
The title compound was prepared according to the general procedure in Example 1 using 2-(6-bromopyridin-2-yl)-2-morpholin-4-ylethanol (194 mg, 0.68 mmol) and 2-amino-5-[4-(1-hydroxy-1-methylethyl)phenyl]thiophene-3-carboxamide (190 mg, 0.69 mmol) as the starting materials.
출처 및 근거
- ORD 기록
- ord-cb68c20d32734bc9a195604e97df4b30
- 출처 데이터셋
- uspto-grants-2013_02