Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
N-(3-Chloro-4-fluorophenyl)-6,7-dihydro-5H-pyrrolo[3',4':4,5]thieno[2,3-d]pyrimidin-4-amine → HCID 58116848, 화합물
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | N-(3-Chloro-4-fluorophenyl)-6,7-dihydro-5H-pyrrolo[3',4':4,5]thieno[2,3-d]pyrimidin-4-amine | HCID 58116969 | — |
| 반응물 | (2E)-4-[methyl(1-methylethyl)amino]but-2-enoic acid hydrochloride | HCID 86650197 | — |
| 생성물 | HCID 58116848 | HCID 58116848 | — |
반응 단계
In analogy to Example 89, the title compound was prepared from N-(3-chloro-4-fluorophenyl)-6,7-dihydro-5H-pyrrolo[3′,4′:4,5]thieno[2,3-d]pyrimidin-4-amine from Example 23A (60 mg, 0.19 mmol) and (2E)-4-[methyl(1-methylethyl)amino]but-2-enoic acid hydrochloride from Example 2A (51 mg, 0.26 mmol) to yield 30 mg (35%).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08524722B2 |
| 출처 데이터셋 | uspto-grants-2013_09 |
| ORD ID | ord-5cfaa2797eb74eff872218a01a59f944 |
| 출처 메모 | uspto-grants-2013_09 |