2-(6-Bromopyridin-2-yl)ethanol → 2-Bromo-6-{2-[(3-methyl-1,2,4-oxadiazol-5-yl)methoxy]ethyl}pyridine

HRID 385860노트

반응식

HRID 385860 반응식
[Br:1][C:2]1[N:7]=[C:6]([CH2:8][CH2:9][OH:10])[CH:5]=[CH:4][CH:3]=1.I[CH2:12][C:13]1[O:17][N:16]=[C:15]([CH3:18])[N:14]=1>>[Br:1][C:2]1[CH:3]=[CH:4][CH:5]=[C:6]([CH2:8][CH2:9][O:10][CH2:12][C:13]2[O:17][N:16]=[C:15]([CH3:18])[N:14]=2)[N:7]=1

참가 물질

3

반응물 2

HCID 468357132-(6-Bromopyridin-2-yl)ethanolHCID 595258535-(Iodomethyl)-3-methyl-1,2,4-oxadiazole

생성물 1

HCID 595256932-Bromo-6-{2-[(3-methyl-1,2,4-oxadiazol-5-yl)methoxy]ethyl}pyridine

실험 절차

The title compound was prepared as described in Example 236, Step 1 using 2-(6-bromopyridin-2-yl)ethanol (Example 235 Step 3) (50 mg, 0.25 mmol) and 5-(iodomethyl)-3-methyl-1,2,4-oxadiazole (110 mg, 0.50 mmol) as starting materials.

출처 및 근거

ORD 기록
ord-0acce31e1dcd44c8ad19cd2a2b249081
출처 데이터셋
uspto-grants-2013_02
특허 번호
US08367706B2

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