HCID 15325851, 화합물 → HCID 59526277, 화합물

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[NH2:1][C:2]1[S:3][C:4]([C:10]2[C:15]([F:16])=[CH:14][C:13]([C:17]([OH:20])([CH3:19])[CH3:18])=[CH:12][C:11]=2[F:21])=[CH:5][C:6]=1[C:7]([NH2:9])=[O:8].Br[C:23]1[N:28]=[C:27]([C:29]2[CH:34]=[CH:33][C:32](=[O:35])[N:31]([CH3:36])[CH:30]=2)[CH:26]=[CH:25][CH:24]=1>>[F:16][C:15]1[CH:14]=[C:13]([C:17]([OH:20])([CH3:18])[CH3:19])[CH:12]=[C:11]([F:21])[C:10]=1[C:4]1[S:3][C:2]([NH:1][C:23]2[N:28]=[C:27]([C:29]3[CH:34]=[CH:33][C:32](=[O:35])[N:31]([CH3:36])[CH:30]=3)[CH:26]=[CH:25][CH:24]=2)=[C:6]([C:7]([NH2:9])=[O:8])[CH:5]=1

참가 물질

반응물 2

HCID 15325851HCID 15325851, 화합물

HCID 595256192-Amino-5-[2,6-difluoro-4-(1-hydroxy-1-methylethyl)phenyl]thiophene-3-carboxamide

생성물 1

HCID 59526277HCID 59526277, 화합물

실험 절차

The title compound was prepared as described in Example 1 using 2-amino-5-[2,6-difluoro-4-(1-hydroxy-1-methylethyl)phenyl]thiophene-3-carboxamide (38 mg, 0.12 mmol) and 6-bromo-1′-methyl-2,3′-bipyridin-6′(1′H)-one (33 mg, 0.12 mmol) as starting materials.

출처 및 근거

ORD 기록: ord-14a8b5c266eb455ebde91eb16df8eca6
출처 데이터셋: uspto-grants-2013_02
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US08367706B2

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