2-Chloropyrimidine-4,5-diamine → 8-(2-Methoxy-4-benzyloxy-phenyl)-2-chloro-purine

반응식

[Cl:1][C:2]1[N:7]=[C:6]([NH2:8])[C:5]([NH2:9])=[CH:4][N:3]=1.[CH3:10][O:11][C:12]1[CH:20]=[C:19]([O:21][CH2:22][C:23]2[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=2)[CH:18]=[CH:17][C:13]=1[C:14](O)=O>>[CH3:10][O:11][C:12]1[CH:20]=[C:19]([O:21][CH2:22][C:23]2[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=2)[CH:18]=[CH:17][C:13]=1[C:14]1[NH:9][C:5]2[C:6](=[N:7][C:2]([Cl:1])=[N:3][CH:4]=2)[N:8]=1

참가 물질

반응물 2

HCID 845652-Chloropyrimidine-4,5-diamine

HCID 64834084-Benzyloxy-2-methoxy-benzoic acid

생성물 1

HCID 135323868-(2-Methoxy-4-benzyloxy-phenyl)-2-chloro-purine

실험 절차

Prepared analogously to Example 5 from 2-chloro-4,5-diaminopyrimidine and 2-methoxy-4-benzyloxy benzoic acid.

출처 및 근거

ORD 기록: ord-1cb12684952945bc8c6d959e38d194f3
출처 데이터셋: uspto-grants-1988_02
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US04722929

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