2,2,2-Trifluoroethanethiol → [6-Methoxy-2'-(2,2,2-trifluoro-ethylsulfanylmethyl)-4'-trifluoromethyl-biphenyl-3-yl]-acetic acid ethyl ester

HRID 38692노트

반응식

HRID 38692 반응식
[CH2:1]([O:3][C:4](=[O:26])[CH2:5][C:6]1[CH:7]=[C:8]([C:14]2[CH:19]=[CH:18][C:17]([C:20]([F:23])([F:22])[F:21])=[CH:16][C:15]=2[CH2:24]Br)[C:9]([O:12][CH3:13])=[CH:10][CH:11]=1)[CH3:2].[F:27][C:28]([F:32])([F:31])[CH2:29][SH:30]>>[CH2:1]([O:3][C:4](=[O:26])[CH2:5][C:6]1[CH:7]=[C:8]([C:14]2[CH:19]=[CH:18][C:17]([C:20]([F:23])([F:22])[F:21])=[CH:16][C:15]=2[CH2:24][S:30][CH2:29][C:28]([F:32])([F:31])[F:27])[C:9]([O:12][CH3:13])=[CH:10][CH:11]=1)[CH3:2]

참가 물질

3

반응물 2

HCID 41339242,2,2-TrifluoroethanethiolHCID 67430388(2'-Bromomethyl-6-methoxy-4'-trifluoromethyl-biphenyl-3-yl)-acetic acid ethyl ester

생성물 1

HCID 86658174[6-Methoxy-2'-(2,2,2-trifluoro-ethylsulfanylmethyl)-4'-trifluoromethyl-biphenyl-3-yl]-acetic acid ethyl ester

실험 절차

Prepared according to the procedure described in Example 1, Step 6, using the following starting materials: (2′-bromomethyl-6-methoxy-4′-trifluoromethyl-biphenyl-3-yl)-acetic acid ethyl ester and 2,2,2-trifluoroethanethiol.

후처리

  1. customPrepared

출처 및 근거

ORD 기록
ord-8219262abc0243eb8a55f03ff6d39d3e
출처 데이터셋
uspto-grants-2013_09
특허 번호
US08524748B2

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