Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Benzyl azide → 4-(1-benzyl-1H-1,2,3-triazol-5-yl)benzaldehyde
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Benzyl azide | HCID 12152 | — |
| 반응물 | 4-Ethynylbenzaldehyde | HCID 2771645 | — |
| 촉매 | Chlororuthenium(1+) 1,2,3,4,5-pentamethylcyclopenta-2,4-dien-1-ide--triphenylphosphane (1/1/2) | HCID 71310463 | — |
| 용매 | Benzene | HCID 241 | — |
| 생성물 | 4-(1-benzyl-1H-1,2,3-triazol-5-yl)benzaldehyde | HCID 11680523 | — |
반응 단계
Benzyl azide (0.200 g, 1.50 mmol), 4-ethynylbenzaldehyde (0.200 g, 1.54 mmol), Cp*RuCl(PPh3)2 (25 mg, 0.031 mmol). Solvent, benzene; reaction temperature, 80° C.; reaction time, 2 hours; yield, 0.32 g (81%). EI-MS: m/z 264 [M+1].
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08372986B2 |
| 출처 데이터셋 | uspto-grants-2013_02 |
| ORD ID | ord-f8cb6781f79b4e22a85b531c4ad50dd2 |
| 출처 메모 | uspto-grants-2013_02 |