Methylamine → 2-Methoxy-8-(2-methoxy-4-chloro-5-methylaminosulfonyl-phenyl)-purine

HRID 3879노트

반응식

HRID 3879 반응식
[CH3:1][O:2][C:3]1[N:11]=[C:10]2[C:6]([NH:7][C:8]([C:12]3[CH:17]=[C:16]([S:18](Cl)(=[O:20])=[O:19])[C:15]([Cl:22])=[CH:14][C:13]=3[O:23][CH3:24])=[N:9]2)=[CH:5][N:4]=1.[CH3:25][NH2:26]>>[CH3:1][O:2][C:3]1[N:11]=[C:10]2[C:6]([NH:7][C:8]([C:12]3[CH:17]=[C:16]([S:18]([NH:26][CH3:25])(=[O:20])=[O:19])[C:15]([Cl:22])=[CH:14][C:13]=3[O:23][CH3:24])=[N:9]2)=[CH:5][N:4]=1

참가 물질

3

반응물 2

HCID 6329MethylamineHCID 201532852-Methoxy-8-(2-methoxy-4-chloro-5-chlorosulfonyl-phenyl)-purine

생성물 1

HCID 201532462-Methoxy-8-(2-methoxy-4-chloro-5-methylaminosulfonyl-phenyl)-purine

실험 절차

Prepared analogously to Example 11 from 2-methoxy-8-(2-methoxy-4-chloro-5-chlorosulfonyl-phenyl)-purine and aqueous methylamine solution.

출처 및 근거

ORD 기록
ord-07ba6e5f908b4ae49ca949e471af2338
출처 데이터셋
uspto-grants-1988_02
특허 번호
US04722929

반응 노트

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