Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Oxiranemethanol, 4-methylbenzenesulfonate, (S)- → 4-(4-amino-3-chlorophenoxy)-6-cyano-7-((2S)-oxiran-2-yl)methoxyquinoline
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Oxiranemethanol, 4-methylbenzenesulfonate, (S)- | HCID 153296 | — |
| 반응물 | 4-(4-Amino-3-chlorophenoxy)-6-cyano-7-hydroxyquinoline | HCID 135829387 | — |
| 생성물 | 4-(4-amino-3-chlorophenoxy)-6-cyano-7-((2S)-oxiran-2-yl)methoxyquinoline | HCID 86591468 | 12.5% |
반응 단계
The title compound (147 mg, 0.400 mmol, 12.5%) was obtained as light brown crystals from a 4-(4-amino-3-chlorophenoxy)-6-cyano-7-hydroxyquinoline crude product (1.00 g, 3.21 mmol) and (2S)-oxiran-2-ylmethyl 4-methyl-1-benzene sulfonate, by the same procedure as in Example 7.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08372981B2 |
| 출처 데이터셋 | uspto-grants-2013_02 |
| ORD ID | ord-adeec8a5010846da8bd8e69b3c5903a4 |
| 출처 메모 | uspto-grants-2013_02 |