5,6-Diamino-1,3-dimethyluracil → 1,3-Dimethyl-8-(2-methoxy-4-benzyloxy-phenyl)-1H,3H-purin-2,6-dione

반응식

[CH3:1][N:2]1[C:7](=[O:8])[C:6]([NH2:9])=[C:5]([NH2:10])[N:4]([CH3:11])[C:3]1=[O:12].[CH3:13][O:14][C:15]1[CH:23]=[C:22]([O:24][CH2:25][C:26]2[CH:31]=[CH:30][CH:29]=[CH:28][CH:27]=2)[CH:21]=[CH:20][C:16]=1[C:17](O)=O>>[CH3:1][N:2]1[C:7](=[O:8])[C:6]2[NH:9][C:17]([C:16]3[CH:20]=[CH:21][C:22]([O:24][CH2:25][C:26]4[CH:27]=[CH:28][CH:29]=[CH:30][CH:31]=4)=[CH:23][C:15]=3[O:14][CH3:13])=[N:10][C:5]=2[N:4]([CH3:11])[C:3]1=[O:12]

참가 물질

반응물 2

HCID 795015,6-Diamino-1,3-dimethyluracil

HCID 64834084-Benzyloxy-2-methoxy-benzoic acid

생성물 1

HCID 201532171,3-Dimethyl-8-(2-methoxy-4-benzyloxy-phenyl)-1H,3H-purin-2,6-dione

실험 절차

Prepared analogously to Example 14 from 1,3-dimethyl-4,5-diamino-1H,3H-pyrimidin-2,6-dione and 2-methoxy-4-benzyloxybenzoic acid.

출처 및 근거

ORD 기록: ord-66ffec08e9f549e2bbc01b436836183e
출처 데이터셋: uspto-grants-1988_02
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US04722929

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