4,5-Pyrimidinediamine, 6-chloro- → 6-Chloro-8-(2,4-dimethoxy-5-bromo-phenyl)-purine

반응식

[NH2:1][C:2]1[C:7]([NH2:8])=[C:6]([Cl:9])[N:5]=[CH:4][N:3]=1.[CH3:10][O:11][C:12]1[CH:20]=[C:19]([O:21][CH3:22])[C:18]([Br:23])=[CH:17][C:13]=1[C:14](O)=O>>[Cl:9][C:6]1[N:5]=[CH:4][N:3]=[C:2]2[C:7]=1[NH:8][C:14]([C:13]1[CH:17]=[C:18]([Br:23])[C:19]([O:21][CH3:22])=[CH:20][C:12]=1[O:11][CH3:10])=[N:1]2

참가 물질

반응물 2

HCID 780104,5-Pyrimidinediamine, 6-chloro-

HCID 135050975-Bromo-2,4-dimethoxybenzoic acid

생성물 1

HCID 201532746-Chloro-8-(2,4-dimethoxy-5-bromo-phenyl)-purine

실험 절차

Prepared analogously to Example 14 from 4,5-diamino-6-chloropyrimidine and 2,4-dimethoxy-5-bromo-benzoic acid.

출처 및 근거

ORD 기록: ord-812dd49b20de4a6eb087670e6fda7435
출처 데이터셋: uspto-grants-1988_02
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US04722929

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