Quinoline → 7-Bromo-4-iodoquinoline

HRID 388628

반응식

[Br:1][C:2]1[CH:3]=[C:4]([CH:6]=[CH:7][CH:8]=1)[NH2:5].[I:9][C:10]1[CH:19]=[CH:18]C2C(=CC=CC=2)N=1.N1C2C(=CC=CC=2)C=CC=1>>[Br:1][C:2]1[CH:3]=[C:4]2[C:6]([C:10]([I:9])=[CH:19][CH:18]=[N:5]2)=[CH:7][CH:8]=1

참가 물질

반응물 3

HCID 7047Quinoline

HCID 115623-Bromoaniline

HCID 810442-Iodoquinoline

생성물 1

HCID 177505937-Bromo-4-iodoquinoline

실험 절차

The 7-bromo-4-iodoquinoline 40a is synthesized from 3-bromoaniline using the same protocols as those described for the preparation of iodoquinoline fragment 1i in Example 1.

출처 및 근거

ORD 기록: ord-97302ae2cb554c30adf00e17e719d2d7
출처 데이터셋: uspto-grants-2013_02
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US08377960B2

연결된 노트

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