참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Water | HCID 962 | — |
| 반응물 | Acetic Anhydride | HCID 7918 | — |
| 반응물 | Sodium Acetate | HCID 517045 | — |
| 반응물 | 3-Methylsalicylaldehyde | HCID 522777 | — |
| 용매 | Hexane | HCID 8058 | — |
| 생성물 | 8-Methylcoumarin | HCID 15734 | 85% |
반응 단계
The suspension of 2-Hydroxy-3-methyl benzaldehyde (30 gm, 0.220 mole) and anhydrous Sodium acetate (45 gm, 0.55 mole) in Acetic anhydride (45 gm, 0.44 mole) was heated at 175-180° C. for 6 hours. The reaction mixture was cooled; water (150 ml) and Hexane (60 ml) were added. It was stirred for an hour and filtered. The obtained solid was stirred with Diethyl ether (30 ml). Finally the suspension was filtered and dried to give 19 gm desired product.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US08378118B2 |
|---|
| 출처 데이터셋 | uspto-grants-2013_02 |
|---|
| ORD ID | ord-58d0d4d5d47848f591413a9b1a765b8b |
|---|
| 출처 메모 | uspto-grants-2013_02 |
|---|
