Bis(pentafluoroethyl)phosphinic acid → Bis(pentafluoroethyl)phosphinyl chloride

반응식

[F:1][C:2]([P:8]([C:11]([F:17])([F:16])[C:12]([F:15])([F:14])[F:13])(=O)[OH:9])([F:7])[C:3]([F:6])([F:5])[F:4].C1(P(Cl)(Cl)(Cl)[Cl:25])C=CC=CC=1>>[F:1][C:2]([P:8]([Cl:25])([C:11]([F:17])([F:16])[C:12]([F:15])([F:14])[F:13])=[O:9])([F:7])[C:3]([F:6])([F:5])[F:4]

참가 물질

반응물 2

HCID 11653013Bis(pentafluoroethyl)phosphinic acid

HCID 12468899Phenylphosphorus tetrachloride

생성물 1

HCID 14294485Bis(pentafluoroethyl)phosphinyl chloride수율 78.4%

실험 절차

21.75 g (72 mmol) of bis(pentafluoroethyl)phosphinic acid are added dropwise at room temperature to 20.0 g (80 mmol) of phenyltetrachlorophosphorane, and the mixture is stirred for four hours. Bis(pentafluoroethyl)phosphinyl chloride is separated off by distillation at atmospheric pressure, giving 18.1 g of bis(pentafluoroethyl)phosphinyl chloride, which corresponds to a yield of 78%, based on the phosphinic acid employed.

후처리

customBis(pentafluoroethyl)phosphinyl chloride is separated off by distillation at atmospheric pressure

출처 및 근거

ORD 기록: ord-e071eabe65f5416db0eaf32f299ac32a
출처 데이터셋: uspto-grants-2013_02
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US08378157B2

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