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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 38948생성일: 2026년 10월 25일

1-Propanamine, N-ethyl- → N-Ethyl-N-{[(2S)-5-chloro-7-(methylsulfonyl)-2,3-dihydro-1,4-benzodioxin-2-YL]methyl}propan-1-amine

https://huagongshe.com/reaction/38948

반응식

참여 물질

역할이름HCID투입량
반응물1-Propanamine, N-ethyl-HCID 88398—
반응물[(2R)-5-chloro-7-(methylsulfonyl)-2,3-dihydro-1,4-benzodioxin-2-yl]methyl 4-methylbenzenesulfonateHCID 86652939—
용매AcetonitrileHCID 6342—
생성물N-Ethyl-N-{[(2S)-5-chloro-7-(methylsulfonyl)-2,3-dihydro-1,4-benzodioxin-2-YL]methyl}propan-1-amineHCID 67199634—

반응 단계

Preparation according to Example 57 using [(2R)-5-chloro-7-(methylsulfonyl)-2,3-dihydro-1,4-benzodioxin-2-yl]methyl 4-methylbenzenesulfonate (0.027 g, 0.062 mmol), N-ethylpropan-1-amine (0.5 ml), ACN (3 ml). MS m/z (rel. intensity, 70 eV) 347 (M+, 0.2), 101 (7), 100 (bp), 98 (5), 72 (8), 58 (9).

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US08524766B2
출처 데이터셋uspto-grants-2013_09
ORD IDord-7f68cfbe9e8e4e7f854fbaf9a291f340
출처 메모uspto-grants-2013_09