Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
N-Methylethylamine → N-{[(2S)-5-Chloro-7-(methylsulfonyl)-2,3-dihydro-1,4-benzodioxin-2-YL]methyl}-N-methylethanamine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | N-Methylethylamine | HCID 12219 | — |
| 반응물 | [(2R)-5-chloro-7-(methylsulfonyl)-2,3-dihydro-1,4-benzodioxin-2-yl]methyl 4-methylbenzenesulfonate | HCID 86652939 | — |
| 용매 | Acetonitrile | HCID 6342 | — |
| 생성물 | N-{[(2S)-5-Chloro-7-(methylsulfonyl)-2,3-dihydro-1,4-benzodioxin-2-YL]methyl}-N-methylethanamine | HCID 44468244 | — |
반응 단계
Preparation according to Example 57 using [(2R)-5-chloro-7-(methylsulfonyl)-2,3-dihydro-1,4-benzodioxin-2-yl]methyl 4-methylbenzenesulfonate (0.027 g, 0.062 mmol), N-methylethanamine (0.5 ml), ACN (3 ml). MS m/z (rel. intensity, 70 eV) 319 (M+, 0.3), 85 (3), 84 (3), 73 (5), 72 (bp), 63 (2).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08524766B2 |
| 출처 데이터셋 | uspto-grants-2013_09 |
| ORD ID | ord-0b11b57e306f4930a0001484a8ee8958 |
| 출처 메모 | uspto-grants-2013_09 |