Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
3-Methylacetophenone → 2-Bromo-1-(3-methylphenyl)ethan-1-one
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 3-Methylacetophenone | HCID 11455 | — |
| 반응물 | Bromine | HCID 24408 | — |
| 반응물 | Sodium Bicarbonate | HCID 516892 | — |
| 용매 | Diethyl Ether | HCID 3283 | — |
| 생성물 | 2-Bromo-1-(3-methylphenyl)ethan-1-one | HCID 10036129 | — |
반응 단계
To a solution of 1-(3-methylphenyl)ethanone (2 g) in ethyl ether (20 mL) is added bromine (726 μL) at 0° C. The mixture is treated with an aqueous solution of sodium bicarbonate, extracted with ethyl ether, dried over magnesium sulfate, concentrated and purified on silica gel (ethyl acetate/cyclohexane 0/100) to give the desired compound.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08383608B2 |
| 출처 데이터셋 | uspto-grants-2013_02 |
| ORD ID | ord-6dd5181a9b7a47fb8fad3019836c489d |
| 출처 메모 | uspto-grants-2013_02 |