Trifluoroacetic acid → HCID 44818188, 화합물

HRID 390055노트

반응식

HRID 390055 반응식
[CH3:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[NH:8][C:9]1[C:10]2[C:20](=[O:21])[NH:19][CH:18]=[CH:17][C:11]=2[N:12]=[C:13](SC)[N:14]=1.C1C=C(Cl)C=C(C(OO)=O)C=1.[NH2:33][CH2:34][CH2:35][CH2:36][NH:37]C(=O)OC(C)(C)C.C(O)(C(F)(F)F)=O>>[NH2:33][CH2:34][CH2:35][CH2:36][NH:37][C:13]1[N:14]=[C:9]([NH:8][C:3]2[CH:4]=[CH:5][CH:6]=[CH:7][C:2]=2[CH3:1])[C:10]2[C:20](=[O:21])[NH:19][CH:18]=[CH:17][C:11]=2[N:12]=1

참가 물질

4

반응물 3

HCID 6422Trifluoroacetic acidHCID 58296339HCID 58296339, 화합물HCID 86654203HCID 86654203, 화합물

생성물 1

HCID 44818188HCID 44818188, 화합물

실험 절차

The compound was prepared from 4-[(2-methylphenyl)amino]-2-(methylthio)pyrido[4,3-d]pyrimidin-5(6H)-one following a procedure (mCPBA/1,1-dimethylethyl (3-aminopropyl)carbamate and TFA) similar to that described for Example 1 (Scheme 2).

출처 및 근거

ORD 기록
ord-4059ec80b0df4a9f89dd5156db8c4aaa
출처 데이터셋
uspto-grants-2013_02
특허 번호
US08383635B2

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