5-Amino-1,3-dihydro-2lambda6-benzothiophene-2,2-dione → 4-[(2,2-Dioxido-1,3-dihydro-2-benzothien-5-yl)amino]-6-methyl-2-(methylthio)-5-pyrimidinecarbonitrile

HRID 390056노트

반응식

HRID 390056 반응식
Cl[C:2]1[C:7]([C:8]#[N:9])=[C:6]([CH3:10])[N:5]=[C:4]([S:11][CH3:12])[N:3]=1.[O:13]=[S:14]1(=[O:24])[CH2:18][C:17]2[CH:19]=[CH:20][C:21]([NH2:23])=[CH:22][C:16]=2[CH2:15]1>>[O:13]=[S:14]1(=[O:24])[CH2:18][C:17]2[CH:19]=[CH:20][C:21]([NH:23][C:2]3[C:7]([C:8]#[N:9])=[C:6]([CH3:10])[N:5]=[C:4]([S:11][CH3:12])[N:3]=3)=[CH:22][C:16]=2[CH2:15]1

참가 물질

3

반응물 2

HCID 28219175-Amino-1,3-dihydro-2lambda6-benzothiophene-2,2-dioneHCID 582963084-Chloro-6-methyl-2-(methylthio)pyrimidine-5-carbonitrile

생성물 1

HCID 582963244-[(2,2-Dioxido-1,3-dihydro-2-benzothien-5-yl)amino]-6-methyl-2-(methylthio)-5-pyrimidinecarbonitrile

실험 절차

The compound was prepared from 4-chloro-6-methyl-2-(methylthio)-5-pyrimidinecarbonitrile and (2,2-dioxido-1,3-dihydro-2-benzothien-5-yl)amine following a procedure similar to that described for Intermediate 23.

출처 및 근거

ORD 기록
ord-d8870da9a0964a96b527e6164d8f2344
출처 데이터셋
uspto-grants-2013_02
특허 번호
US08383635B2

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