HCID 44818005, 화합물 → HCID 67221700, 화합물

반응식

[NH2:1][CH2:2][CH2:3][CH2:4][NH:5][C:6]1[N:7]=[C:8]([NH:17][C:18]2[CH:23]=[CH:22][CH:21]=[C:20]([CH3:24])[CH:19]=2)[C:9]2[C:15](=[O:16])[NH:14][CH:13]=[CH:12][C:10]=2[N:11]=1.NCCCN[C:30]([C@@H:32]1[CH2:36][S:35][C:34](=[O:37])[NH:33]1)=[O:31]>>[CH3:24][C:20]1[CH:19]=[C:18]([NH:17][C:8]2[C:9]3[C:15](=[O:16])[NH:14][CH:13]=[CH:12][C:10]=3[N:11]=[C:6]([NH:5][CH2:4][CH2:3][CH2:2][NH:1][C:30]([C@@H:32]3[CH2:36][S:35][C:34](=[O:37])[NH:33]3)=[O:31])[N:7]=2)[CH:23]=[CH:22][CH:21]=1

참가 물질

반응물 2

HCID 44818005HCID 44818005, 화합물

HCID 67221680HCID 67221680, 화합물

생성물 1

HCID 67221700HCID 67221700, 화합물

실험 절차

The compound was prepared from 2-[(3-aminopropyl)amino]-4-[(3-methylphenyl)amino]pyrido[4,3-d]pyrimidin-5(6H)-one and (4R)—N-(3-aminopropyl)-2-oxo-1,3-thiazolidine-4-carboxamide using the procedure similar to that described for Example

출처 및 근거

ORD 기록: ord-d7a5ebbca7c741088662b3bc40d0783e
출처 데이터셋: uspto-grants-2013_02
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US08383635B2

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