Ammonia → HCID 44546230, 화합물

HRID 390451

반응식

HRID 390451 반응식
[OH:1][N:2]=[C:3](Cl)[C:4]1[CH:9]=[CH:8][CH:7]=[N:6][CH:5]=1.[C:11]([C:13]1[CH:14]=[C:15]([CH:18]=[CH:19][CH:20]=1)[C:16]#[N:17])#[CH:12].N>>[N:6]1[CH:7]=[CH:8][CH:9]=[C:4]([C:3]2[CH:12]=[C:11]([C:13]3[CH:14]=[C:15]([CH:18]=[CH:19][CH:20]=3)[C:16]#[N:17])[O:1][N:2]=2)[CH:5]=1

참가 물질

4

반응물 3

HCID 222AmmoniaHCID 120889643-EthynylbenzonitrileHCID 53404818N-Hydroxy-3-pyridinecarboximidoyl chloride

생성물 1

HCID 44546230HCID 44546230, 화합물

실험 절차

The titled compound was prepared according to Method CB using the product of Example 1A (78 mg, 0.5 mmol) and the product of Example 19A (64 mg, 0.5 mmol). 1H NMR (300 MHz, MeOH-d4) 87.53 (s, 1H), 7.61 (ddd, J=8.1, 5.0, 0.8 Hz, 1H), 7.75 (t, J=7.8 Hz, 1H), 7.88 (dt, J=7.7, 1.4 Hz, 1H), 8.23 (dt, J=8.1, 1.4 Hz, 1H), 8.31 (t, J=1.7 Hz, 1H), 8.38 (dt, J=8.1, 1.9 Hz, 1H), 8.68 (dd, J=5.1, 1.7 Hz, 1H), 9.10 (d, J=2.0 Hz, 1H) ppm; MS (DCI/NH3) m/z 248 (M+H)+.

출처 및 근거

ORD 기록
ord-b1b41d70655f425087946eb5c818ffb9
출처 데이터셋
uspto-grants-2013_02
특허 번호
US08383658B2

연결된 노트

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