Ammonia → HCID 44546415, 화합물

HRID 390477

반응식

HRID 390477 반응식
[OH:1][N:2]=[C:3](Cl)[C:4]1[CH:5]=[N:6][CH:7]=[N:8][CH:9]=1.[C:11]([C:13]1[CH:14]=[C:15]([CH:18]=[CH:19][CH:20]=1)[C:16]#[N:17])#[CH:12].N>>[N:6]1[CH:5]=[C:4]([C:3]2[CH:12]=[C:11]([C:13]3[CH:14]=[C:15]([CH:18]=[CH:19][CH:20]=3)[C:16]#[N:17])[O:1][N:2]=2)[CH:9]=[N:8][CH:7]=1

참가 물질

4

반응물 3

HCID 222AmmoniaHCID 120889643-EthynylbenzonitrileHCID 86636847N-Hydroxypyrimidine-5-carbimidoyl chloride

생성물 1

HCID 44546415HCID 44546415, 화합물

실험 절차

The titled compound was prepared as the hydrochloride salt according to Method CB using the product of Example 44B (79 mg, 0.5 mmol) and the product of Example 19A (64 mg, 0.5 mmol). 1H NMR (300 MHz, DMSO-d6) δ 7.83 (t, J=7.8 Hz, 1H), 7.94 (s, 1H), 8.04 (dt, J=7.8, 1.4 Hz, 1H), 8.25 (dt, J=8.1, 1.4 Hz, 1H), 8.42 (t, J=1.5 Hz, 1H), 9.32 (s, 2H), 9.36 (s, 1H) ppm; MS (DCI/NH3) m/z 249 (M+H)+.

출처 및 근거

ORD 기록
ord-4288092cf4314dc1bfe38a122b8748c8
출처 데이터셋
uspto-grants-2013_02
특허 번호
US08383658B2

연결된 노트

불러오는 중…